2c0t
From Proteopedia
(Difference between revisions)
Line 2: | Line 2: | ||
<StructureSection load='2c0t' size='340' side='right' caption='[[2c0t]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='2c0t' size='340' side='right' caption='[[2c0t]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2c0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2c0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C0T FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=L3G:N-(4-{4-AMINO-1-[1-(TETRAHYDRO-2H-PYRAN-4-YL)PIPERIDIN-4-YL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE'>L3G</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=L3G:N-(4-{4-AMINO-1-[1-(TETRAHYDRO-2H-PYRAN-4-YL)PIPERIDIN-4-YL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE'>L3G</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ad5|1ad5]], [[1bu1|1bu1]], [[1qcf|1qcf]], [[2c0i|2c0i]], [[2c0o|2c0o]], [[2hck|2hck]], [[3hck|3hck]], [[4hck|4hck]], [[5hck|5hck]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ad5|1ad5]], [[1bu1|1bu1]], [[1qcf|1qcf]], [[2c0i|2c0i]], [[2c0o|2c0o]], [[2hck|2hck]], [[3hck|3hck]], [[4hck|4hck]], [[5hck|5hck]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c0t RCSB], [http://www.ebi.ac.uk/pdbsum/2c0t PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c0t OCA], [http://pdbe.org/2c0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c0t RCSB], [http://www.ebi.ac.uk/pdbsum/2c0t PDBsum]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
Line 27: | Line 27: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 2c0t" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
Line 34: | Line 35: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Human]] |
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Borhani, D W]] | [[Category: Borhani, D W]] |
Revision as of 22:41, 10 September 2015
SRC FAMILY KINASE HCK WITH BOUND INHIBITOR A-641359
|
Categories: Human | Transferase | Borhani, D W | Burchat, A | Calderwood, D J | Hirst, G C | Li, B | Loew, A | Atp-binding | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Palmitate | Sh2 domain | Sh3 domain