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2c27
From Proteopedia
(Difference between revisions)
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<StructureSection load='2c27' size='340' side='right' caption='[[2c27]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2c27' size='340' side='right' caption='[[2c27]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2c27]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2c27]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C27 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C27 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MA8:(2S,3R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL+2-(L-CYSTEINYLAMINO)-2-DEOXY-ALPHA-L-GLUCOPYRANOSIDE'>MA8</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MA8:(2S,3R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL+2-(L-CYSTEINYLAMINO)-2-DEOXY-ALPHA-L-GLUCOPYRANOSIDE'>MA8</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ozp|1ozp]], [[1p0h|1p0h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ozp|1ozp]], [[1p0h|1p0h]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c27 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c27 RCSB], [http://www.ebi.ac.uk/pdbsum/2c27 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c27 OCA], [http://pdbe.org/2c27 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c27 RCSB], [http://www.ebi.ac.uk/pdbsum/2c27 PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MSHD_MYCTU MSHD_MYCTU]] Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.<ref>PMID:12375100</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2c27" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Myctu]] |
[[Category: Blanchard, J S]] | [[Category: Blanchard, J S]] | ||
[[Category: Rendle, P M]] | [[Category: Rendle, P M]] | ||
| Line 38: | Line 41: | ||
[[Category: Gcn5 related n- acetyltransferase]] | [[Category: Gcn5 related n- acetyltransferase]] | ||
[[Category: Gnat]] | [[Category: Gnat]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Mycothiol synthase]] | [[Category: Mycothiol synthase]] | ||
[[Category: Synthase]] | [[Category: Synthase]] | ||
Revision as of 01:21, 10 September 2015
THE STRUCTURE OF MYCOTHIOL SYNTHASE IN COMPLEX WITH DES-ACETYLMYCOTHIOL AND COENZYMEA.
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