2ocf
From Proteopedia
(Difference between revisions)
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|PDB= 2ocf |SIZE=350|CAPTION= <scene name='initialview01'>2ocf</scene>, resolution 2.95Å | |PDB= 2ocf |SIZE=350|CAPTION= <scene name='initialview01'>2ocf</scene>, resolution 2.95Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=EST:ESTRADIOL'>EST</scene> | + | |LIGAND= <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=EST:ESTRADIOL'>EST</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CIG, FN1, FN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CIG, FN1, FN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ocf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ocf OCA], [http://www.ebi.ac.uk/pdbsum/2ocf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ocf RCSB]</span> | ||
}} | }} | ||
'''Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody''' | '''Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Ehlers-Danlos syndrome, type X, 225310 (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=135600 135600]], Estrogen resistance OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], HDL response to hormone replacement, augmented OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Migraine, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Myocardial infarction, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Rajan, S S.]] | [[Category: Rajan, S S.]] | ||
[[Category: Sharma, S K.]] | [[Category: Sharma, S K.]] | ||
| - | [[Category: EST]] | ||
[[Category: estradiol]] | [[Category: estradiol]] | ||
[[Category: estrogen receptor]] | [[Category: estrogen receptor]] | ||
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[[Category: monobody]] | [[Category: monobody]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:15:51 2008'' |
Revision as of 01:15, 31 March 2008
| |||||||
| , resolution 2.95Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | ESR1, ESR, NR3A1 (Homo sapiens), CIG, FN1, FN (Homo sapiens) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody
About this Structure
2OCF is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:15:51 2008
