2yr1
From Proteopedia
(Difference between revisions)
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==Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426== | ==Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426== | ||
<StructureSection load='2yr1' size='340' side='right' caption='[[2yr1]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2yr1' size='340' side='right' caption='[[2yr1]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yr1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2yr1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geoka Geoka]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YR1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YR1 FirstGlance]. <br> |
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr> | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yr1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yr1 RCSB], [http://www.ebi.ac.uk/pdbsum/2yr1 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yr1 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yr1 OCA], [http://pdbe.org/2yr1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yr1 RCSB], [http://www.ebi.ac.uk/pdbsum/2yr1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yr1 ProSAT], [http://www.topsan.org/Proteins/RSGI/2yr1 TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AROD_GEOKA AROD_GEOKA]] Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.[HAMAP-Rule:MF_00214] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yr1 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: 3-dehydroquinate dehydratase]] | [[Category: 3-dehydroquinate dehydratase]] | ||
| - | [[Category: | + | [[Category: Geoka]] |
[[Category: Bessho, Y]] | [[Category: Bessho, Y]] | ||
[[Category: Chen, L]] | [[Category: Chen, L]] | ||
Revision as of 12:01, 11 August 2016
Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426
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Categories: 3-dehydroquinate dehydratase | Geoka | Bessho, Y | Chen, L | Chrzas, J | Fu, Z Q | Kagawa, W | Kurumizaka, H | Structural genomic | Wang, B C | Yokoyama, S | 3-dehydroquinase | Amino acid biosynthesis | Lyase | National project on protein structural and functional analyse | Nppsfa | Rsgi
