4qzs

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==Crystal structure of the first bromodomain of human 3-fluoro tyrosine-labeled brd4 in complex with jq1==
==Crystal structure of the first bromodomain of human 3-fluoro tyrosine-labeled brd4 in complex with jq1==
<StructureSection load='4qzs' size='340' side='right' caption='[[4qzs]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='4qzs' size='340' side='right' caption='[[4qzs]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JQ1:(6S)-6-(2-TERT-BUTOXY-2-OXOETHYL)-4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-6,7-DIHYDROTHIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-10-IUM'>JQ1</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JQ1:(6S)-6-(2-TERT-BUTOXY-2-OXOETHYL)-4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-6,7-DIHYDROTHIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-10-IUM'>JQ1</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YOF:3-FLUOROTYROSINE'>YOF</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YOF:3-FLUOROTYROSINE'>YOF</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qzs RCSB], [http://www.ebi.ac.uk/pdbsum/4qzs PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qzs OCA], [http://pdbe.org/4qzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qzs RCSB], [http://www.ebi.ac.uk/pdbsum/4qzs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qzs ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4qzs" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bromodomain-containing protein|Bromodomain-containing protein]]
== References ==
== References ==
<references/>
<references/>

Revision as of 17:46, 11 August 2016

Crystal structure of the first bromodomain of human 3-fluoro tyrosine-labeled brd4 in complex with jq1

4qzs, resolution 1.45Å

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