Acyl-CoA dehydrogenase
From Proteopedia
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| - | '''Acyl-CoA dehydrogenase''' (ACDH) catalyzes the introduction of a double bond between C2 and C3 of the thio-ester CoA substrate. This is the first reaction in fatty acid metabolism which produces acetyl-CoA. FAD is the cofactor of ACDH activity. ACDH is classified according to the length of its substrates as short- (SCAD), medium- (MCAD), very- and very long-chain (VLCAD) ACDH. | + | |
| + | == Function == | ||
| + | |||
| + | '''Acyl-CoA dehydrogenase''' (ACDH) catalyzes the introduction of a double bond between C2 and C3 of the thio-ester CoA substrate. This is the first reaction in fatty acid metabolism which produces acetyl-CoA. FAD is the cofactor of ACDH activity. ACDH is classified according to the length of its substrates as short- (SCAD), medium- (MCAD), very- and very long-chain (VLCAD) ACDH. | ||
| + | |||
| + | == Disease == | ||
| + | |||
| + | Impairment of the activity of ACDH causes a variety of diseases associated with lack of fatty acid metabolism. | ||
==3D structures of acyl-CoA dehydrogenase== | ==3D structures of acyl-CoA dehydrogenase== | ||
Revision as of 09:19, 25 October 2015
Function
Acyl-CoA dehydrogenase (ACDH) catalyzes the introduction of a double bond between C2 and C3 of the thio-ester CoA substrate. This is the first reaction in fatty acid metabolism which produces acetyl-CoA. FAD is the cofactor of ACDH activity. ACDH is classified according to the length of its substrates as short- (SCAD), medium- (MCAD), very- and very long-chain (VLCAD) ACDH.
Disease
Impairment of the activity of ACDH causes a variety of diseases associated with lack of fatty acid metabolism.
3D structures of acyl-CoA dehydrogenase
Updated on 25-October-2015
