2p3u

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|PDB= 2p3u |SIZE=350|CAPTION= <scene name='initialview01'>2p3u</scene>, resolution 1.62&Aring;
|PDB= 2p3u |SIZE=350|CAPTION= <scene name='initialview01'>2p3u</scene>, resolution 1.62&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=663:3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE'>663</scene>
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|LIGAND= <scene name='pdbligand=663:3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE'>663</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=[[2p3t|2p3t]], [[1mq5|1MQ5]], [[1mq6|1MQ6]], [[1fjs|1FJS]], [[1ezq|1EZQ]], [[1f0s|1F0S]], [[1f0r|1F0R]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3u OCA], [http://www.ebi.ac.uk/pdbsum/2p3u PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p3u RCSB]</span>
}}
}}
'''Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}'''
'''Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}'''
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==Disease==
 
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Known disease associated with this structure: Factor X deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227600 227600]]
 
==About this Structure==
==About this Structure==
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[[Category: Adler, M.]]
[[Category: Adler, M.]]
[[Category: Whitlow, M.]]
[[Category: Whitlow, M.]]
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[[Category: 663]]
 
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[[Category: CA]]
 
[[Category: blood clotting]]
[[Category: blood clotting]]
[[Category: coagulation cofactor]]
[[Category: coagulation cofactor]]
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[[Category: protein inhibitor complex]]
[[Category: protein inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:08:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:28:43 2008''

Revision as of 01:28, 31 March 2008


PDB ID 2p3u

Drag the structure with the mouse to rotate
, resolution 1.62Å
Ligands: ,
Activity: Coagulation factor Xa, with EC number 3.4.21.6
Related: 2p3t, 1MQ5, 1MQ6, 1FJS, 1EZQ, 1F0S, 1F0R


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}


About this Structure

2P3U is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 04:28:43 2008

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