2p6x
From Proteopedia
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|PDB= 2p6x |SIZE=350|CAPTION= <scene name='initialview01'>2p6x</scene>, resolution 1.90Å | |PDB= 2p6x |SIZE=350|CAPTION= <scene name='initialview01'>2p6x</scene>, resolution 1.90Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> | + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span> |
|GENE= PTPN22, PTPN8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= PTPN22, PTPN8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2oc3|2OC3]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p6x OCA], [http://www.ebi.ac.uk/pdbsum/2p6x PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p6x RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of human tyrosine phosphatase PTPN22''' | '''Crystal structure of human tyrosine phosphatase PTPN22''' | ||
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| - | ==Disease== | ||
| - | Known diseases associated with this structure: Diabetes mellitus, insulin-dependent, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]], Systemic lupus erythematosus, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Uppenberg, J.]] | [[Category: Uppenberg, J.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: EDO]] | ||
[[Category: lymphoid phosphatase]] | [[Category: lymphoid phosphatase]] | ||
[[Category: lyp]] | [[Category: lyp]] | ||
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[[Category: tyrosine phosphatase]] | [[Category: tyrosine phosphatase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:31:10 2008'' |
Revision as of 01:31, 31 March 2008
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| , resolution 1.90Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | PTPN22, PTPN8 (Homo sapiens) | ||||||
| Activity: | Protein-tyrosine-phosphatase, with EC number 3.1.3.48 | ||||||
| Related: | 2OC3
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of human tyrosine phosphatase PTPN22
About this Structure
2P6X is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:31:10 2008
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Single protein | Alfano, I. | Arrowsmith, C H. | Barr, A. | Bunkoczi, G. | Burgess-Brown, N. | Delft, F von. | Edwards, A. | King, O. | Knapp, S. | Papagrigoriou, E. | Pike, A C.W. | SGC, Structural Genomics Consortium. | Salah, E. | Shrestha, L. | Sundstrom, M. | Turnbull, A. | Ugochukwu, E. | Umeano, C. | Uppenberg, J. | Weigelt, J. | Lymphoid phosphatase | Lyp | Pep | Sgc | Structural genomic | Structural genomics consortium | Tyrosine phosphatase
