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2p8u
From Proteopedia
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|PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00Å | |PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene> | + | |LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10] </span> |
|GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8u OCA], [http://www.ebi.ac.uk/pdbsum/2p8u PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p8u RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I''' | '''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: HMG-CoA synthase-2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600234 600234]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Umeano, C.]] | [[Category: Umeano, C.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| - | [[Category: COA]] | ||
| - | [[Category: GOL]] | ||
[[Category: hydromethylglutaryl coa]] | [[Category: hydromethylglutaryl coa]] | ||
[[Category: mevalonate pathway]] | [[Category: mevalonate pathway]] | ||
| Line 45: | Line 43: | ||
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:32:24 2008'' |
Revision as of 01:32, 31 March 2008
| |||||||
| , resolution 2.00Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | HMGCS1, HMGCS (Homo sapiens) | ||||||
| Activity: | Hydroxymethylglutaryl-CoA synthase, with EC number 2.3.3.10 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I
About this Structure
2P8U is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:32:24 2008
Categories: Homo sapiens | Hydroxymethylglutaryl-CoA synthase | Single protein | Arrowsmith, C H. | Bunkoczi, G. | Burgess, N. | Debreczeni, J. | Delft, F von. | Edwards, A. | Gorrec, F. | Niesen, F H. | Oppermann, U. | Pike, A C.W. | SGC, Structural Genomics Consortium. | Salah, E. | Shafqat, N. | Sundstrom, M. | Turnbull, A P. | Umeano, C. | Weigelt, J. | Hydromethylglutaryl coa | Mevalonate pathway | Sgc | Structural genomic | Structural genomics consortium
