This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Annexin
From Proteopedia
| Line 1: | Line 1: | ||
{{STRUCTURE_1ain| PDB=1ain | SIZE=400| SCENE=Annexin/Cv/2 |right|CAPTION=Human annexin I complex with Ca+2 ions, [[1ain]] }} | {{STRUCTURE_1ain| PDB=1ain | SIZE=400| SCENE=Annexin/Cv/2 |right|CAPTION=Human annexin I complex with Ca+2 ions, [[1ain]] }} | ||
| - | [[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. | + | == Function == |
| + | |||
| + | [[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. Annexins divide into species and are numbered from I to XII. '''Annexin V''' is the most abundant scaffolding protein. '''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls. | ||
| + | |||
| + | == Structural highlights == | ||
| + | |||
| + | Annexins consist of 2 domains - the C-terminal core and the N-terminal head. | ||
==3D structures of annexin== | ==3D structures of annexin== | ||
Revision as of 09:02, 2 November 2015
Function
Annexins are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. Annexin E1 (AnE1) is associated with tubulin in trophozoites of Giardia lamblia and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.
Structural highlights
Annexins consist of 2 domains - the C-terminal core and the N-terminal head.
3D structures of annexin
Updated on 02-November-2015
