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4xvx
From Proteopedia
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| - | ''' | + | ==Crystal structure of an acyl-ACP dehydrogenase== |
| - | + | <StructureSection load='4xvx' size='340' side='right' caption='[[4xvx]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xvx]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4m6z 4m6z]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XVX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FDA:DIHYDROFLAVINE-ADENINE+DINUCLEOTIDE'>FDA</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xvx RCSB], [http://www.ebi.ac.uk/pdbsum/4xvx PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/MBTN_MYCTU MBTN_MYCTU]] Catalyzes the dehydrogenation at the alpha-beta position of ACP-bound acyl chains. This results in the introduction of a double bond in the lipidic chain, which is further transferred to the epsilon-amino group of lysine residue in the mycobactin core by MbtK.<ref>PMID:16461464</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Baker, E N]] | ||
| + | [[Category: Bunker, R D]] | ||
[[Category: Chai, A]] | [[Category: Chai, A]] | ||
| - | [[Category: | + | [[Category: Johnston, J M]] |
| - | [[Category: | + | [[Category: Lott, J S]] |
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Acyl-acp binding]] | ||
| + | [[Category: Dehydrogenation]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Rossmann fold]] | ||
| + | [[Category: Tbsgc]] | ||
Revision as of 11:45, 12 February 2015
Crystal structure of an acyl-ACP dehydrogenase
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