4unl
From Proteopedia
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==Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human== | ==Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human== | ||
<StructureSection load='4unl' size='340' side='right' caption='[[4unl]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='4unl' size='340' side='right' caption='[[4unl]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unk|4unk]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unk|4unk]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4unl RCSB], [http://www.ebi.ac.uk/pdbsum/4unl PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unl OCA], [http://pdbe.org/4unl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4unl RCSB], [http://www.ebi.ac.uk/pdbsum/4unl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4unl ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[http://omim.org/entry/190450 190450]]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. | [[http://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[http://omim.org/entry/190450 190450]]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. | ||
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| + | ==See Also== | ||
| + | *[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 18:06, 11 August 2016
Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human
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