2moc
From Proteopedia
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| - | ''' | + | ==Membrane induced structure of novel human tachykinin Hemokinin-1 (hHK1)== |
| - | + | <StructureSection load='2moc' size='340' side='right' caption='[[2moc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2moc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MOC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MOC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2moc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2moc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2moc RCSB], [http://www.ebi.ac.uk/pdbsum/2moc PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [[ | + | [[http://www.uniprot.org/uniprot/TKN4_HUMAN TKN4_HUMAN]] Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.<ref>PMID:12716968</ref> <ref>PMID:17101218</ref> <ref>PMID:17437961</ref> <ref>PMID:17655832</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Cowsik, S]] | [[Category: Cowsik, S]] | ||
[[Category: Ganjiwale, A]] | [[Category: Ganjiwale, A]] | ||
| + | [[Category: Neuropeptide]] | ||
| + | [[Category: Tachykinin]] | ||
Revision as of 15:55, 27 May 2015
Membrane induced structure of novel human tachykinin Hemokinin-1 (hHK1)
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