2mxr
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase== |
| - | + | <StructureSection load='2mxr' size='340' side='right' caption='[[2mxr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2mxr]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MXR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mxr RCSB], [http://www.ebi.ac.uk/pdbsum/2mxr PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [[ | + | [[http://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN]] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref> |
| - | [ | + | == References == |
| - | [[ | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Alper, S L]] | ||
[[Category: Anklin, C]] | [[Category: Anklin, C]] | ||
| + | [[Category: Birrane, G]] | ||
[[Category: Pollak, M]] | [[Category: Pollak, M]] | ||
| + | [[Category: Rigby, A C]] | ||
| + | [[Category: Sharma, A K]] | ||
| + | [[Category: Protein kinsase g - i alpha]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Vascular smooth muscle cell]] | ||
Revision as of 13:03, 18 February 2015
Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase
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