4k7g
From Proteopedia
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==Crystal structure of a 3-hydroxyproline dehydratse from agrobacterium vitis, target efi-506470, with bound pyrrole 2-carboxylate, ordered active site== | ==Crystal structure of a 3-hydroxyproline dehydratse from agrobacterium vitis, target efi-506470, with bound pyrrole 2-carboxylate, ordered active site== | ||
<StructureSection load='4k7g' size='340' side='right' caption='[[4k7g]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4k7g' size='340' side='right' caption='[[4k7g]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4k7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4k7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrvs Agrvs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K7G FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=PYC:PYRROLE-2-CARBOXYLATE'>PYC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=PYC:PYRROLE-2-CARBOXYLATE'>PYC</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Avi_7022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Avi_7022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=311402 AGRVS])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k7g RCSB], [http://www.ebi.ac.uk/pdbsum/4k7g PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7g OCA], [http://pdbe.org/4k7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k7g RCSB], [http://www.ebi.ac.uk/pdbsum/4k7g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7g ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/T3HPD_AGRVS T3HPD_AGRVS]] Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline. Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity.<ref>PMID:24980702</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Agrvs]] |
[[Category: Almo, S C]] | [[Category: Almo, S C]] | ||
[[Category: Bhosle, R]] | [[Category: Bhosle, R]] | ||
Revision as of 07:28, 23 December 2016
Crystal structure of a 3-hydroxyproline dehydratse from agrobacterium vitis, target efi-506470, with bound pyrrole 2-carboxylate, ordered active site
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Categories: Agrvs | Almo, S C | Bhosle, R | Chowdhury, S | EFI, Enzyme Function Initiative | Evans, B | Gerlt, J A | Glenn, A Scott | Hammonds, J | Hillerich, B | Imker, H J | Love, J | Morisco, L L | Obaidi, N F.Al | Seidel, R D | Sojitra, S | Stead, M | Toro, R | Vetting, M W | Washington, E | Wasserman, S R | Efi | Enzyme function initiative | Isomerase | Proline racemase family | Proposed 3-oh proline dehydratase | Structural genomic
