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2q1b
From Proteopedia
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|PDB= 2q1b |SIZE=350|CAPTION= <scene name='initialview01'>2q1b</scene>, resolution 1.70Å | |PDB= 2q1b |SIZE=350|CAPTION= <scene name='initialview01'>2q1b</scene>, resolution 1.70Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1oq5|1oq5]], [[1z9y|1z9y]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q1b OCA], [http://www.ebi.ac.uk/pdbsum/2q1b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2q1b RCSB]</span> | ||
}} | }} | ||
'''Carbonic Anhydrase II in Complex with Saccharin''' | '''Carbonic Anhydrase II in Complex with Saccharin''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Klebe, G.]] | [[Category: Klebe, G.]] | ||
[[Category: Koehler, K.]] | [[Category: Koehler, K.]] | ||
| - | [[Category: BEZ]] | ||
| - | [[Category: HG]] | ||
| - | [[Category: LSA]] | ||
| - | [[Category: ZN]] | ||
[[Category: 10-stranded]] | [[Category: 10-stranded]] | ||
[[Category: lyase]] | [[Category: lyase]] | ||
[[Category: twisted beta-sheet]] | [[Category: twisted beta-sheet]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:43:26 2008'' |
Revision as of 01:43, 31 March 2008
| |||||||
| , resolution 1.70Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , | ||||||
| Activity: | Carbonate dehydratase, with EC number 4.2.1.1 | ||||||
| Related: | 1oq5, 1z9y
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Carbonic Anhydrase II in Complex with Saccharin
About this Structure
2Q1B is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:17705204
Page seeded by OCA on Mon Mar 31 04:43:26 2008
