4wx2
From Proteopedia
(Difference between revisions)
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- | ''' | + | ==Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with two F6F molecules in the alpha-site and one F6F molecule in the beta-site== |
- | + | <StructureSection load='4wx2' size='340' side='right' caption='[[4wx2]], [[Resolution|resolution]] 1.75Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4wx2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WX2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F6F:2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL+DIHYDROGEN+PHOSPHATE'>F6F</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |
- | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kkx|4kkx]], [[2cle|2cle]], [[2clf|2clf]], [[2clm|2clm]]</td></tr> | |
- | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wx2 OCA], [http://pdbe.org/4wx2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wx2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wx2 PDBsum]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: | + | == Function == |
+ | [[http://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [[http://www.uniprot.org/uniprot/TRPB_SALTY TRPB_SALTY]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Tryptophan synthase]] | ||
+ | [[Category: Caulkins, B G]] | ||
+ | [[Category: Dunn, M F]] | ||
[[Category: Fan, L]] | [[Category: Fan, L]] | ||
- | [[Category: Niks, D]] | ||
- | [[Category: Mueller, L.J]] | ||
- | [[Category: Young, R.P]] | ||
[[Category: Hilario, E]] | [[Category: Hilario, E]] | ||
+ | [[Category: Mueller, L J]] | ||
+ | [[Category: Niks, D]] | ||
+ | [[Category: Young, R P]] | ||
+ | [[Category: Allosteric enzyme]] | ||
+ | [[Category: Aromatic amino acid biosynthesis]] | ||
+ | [[Category: Carbon-oxygen lyase]] | ||
+ | [[Category: F6f]] | ||
+ | [[Category: Inhibitor]] | ||
+ | [[Category: Pyridoxal phosphate]] | ||
+ | [[Category: Salmonella typhimurium]] | ||
+ | [[Category: Transferase]] | ||
+ | [[Category: Tryptophan biosynthesis]] |
Revision as of 18:55, 1 December 2015
Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with two F6F molecules in the alpha-site and one F6F molecule in the beta-site
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Categories: Tryptophan synthase | Caulkins, B G | Dunn, M F | Fan, L | Hilario, E | Mueller, L J | Niks, D | Young, R P | Allosteric enzyme | Aromatic amino acid biosynthesis | Carbon-oxygen lyase | F6f | Inhibitor | Pyridoxal phosphate | Salmonella typhimurium | Transferase | Tryptophan biosynthesis