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4y63

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'''Unreleased structure'''
 
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The entry 4y63 is ON HOLD until Paper Publication
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==AAGlyB in complex with amino-acid analogues==
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<StructureSection load='4y63' size='340' side='right' caption='[[4y63]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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Authors: Wang, S., Cuesta-Seijo, J.A., Striebeck, A., Lafont, D., Palcic, M.M., Vidal, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4y63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y63 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48O:5-DEOXY-5-{[(2S)-2-(TRIAZA-1,2-DIEN-2-IUM-1-YL)PROPANOYL]AMINO}URIDINE'>48O</scene>, <scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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[[Category: Cuesta-Seijo, J.A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y63 OCA], [http://pdbe.org/4y63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y63 RCSB], [http://www.ebi.ac.uk/pdbsum/4y63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y63 ProSAT]</span></td></tr>
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[[Category: Wang, S]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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__TOC__
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</StructureSection>
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[[Category: Human]]
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[[Category: Cuesta-Seijo, J A]]
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[[Category: Lafont, D]]
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[[Category: Palcic, M M]]
[[Category: Striebeck, A]]
[[Category: Striebeck, A]]
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[[Category: Lafont, D]]
 
[[Category: Vidal, S]]
[[Category: Vidal, S]]
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[[Category: Palcic, M.M]]
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[[Category: Wang, S]]
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[[Category: Aaglyb]]
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[[Category: Inhibitor]]
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[[Category: Transferase]]

Revision as of 17:02, 16 November 2017

AAGlyB in complex with amino-acid analogues

4y63, resolution 1.30Å

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