4ycg
From Proteopedia
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| - | ''' | + | ==Pro-bone morphogenetic protein 9== |
| - | + | <StructureSection load='4ycg' size='340' side='right' caption='[[4ycg]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ycg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YCG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ycg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ycg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ycg RCSB], [http://www.ebi.ac.uk/pdbsum/4ycg PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/GDF2_MOUSE GDF2_MOUSE]] Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.<ref>PMID:23300529</ref> [[http://www.uniprot.org/uniprot/GDF2_HUMAN GDF2_HUMAN]] Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks.<ref>PMID:18309101</ref> <ref>PMID:22799562</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Brown, C T]] | ||
| + | [[Category: Gao, Y]] | ||
| + | [[Category: Le, V]] | ||
| + | [[Category: Mi, L Z]] | ||
| + | [[Category: Springer, T A]] | ||
| + | [[Category: Tian, Y]] | ||
| + | [[Category: Walz, T]] | ||
| + | [[Category: Cytokine]] | ||
| + | [[Category: Morphogen]] | ||
| + | [[Category: Pro-bmp complex]] | ||
| + | [[Category: Transforming growth factor-beta family]] | ||
Revision as of 11:40, 4 March 2015
Pro-bone morphogenetic protein 9
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