Carbonyl reductase

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**[[1zze]] – CBR – ''Sporidiobolus salmonicolor''<BR />
**[[1zze]] – CBR – ''Sporidiobolus salmonicolor''<BR />
-
**[[3ctm]] – CBR – ''Candida parapsilosis''<br />
 
**[[3afm]] – SpCBR – ''Sphingomonas''<br />
**[[3afm]] – SpCBR – ''Sphingomonas''<br />
 +
**[[4w7h]] – SpCBR (mutant)<br />
 +
 +
*(R)-specific carbonyl reductase
 +
 +
**[[3ctm]], [[4oaq]] – CpCBR – ''Candida parapsilosis''<br />
 +
**[[3wle]], [[4c4o]] – CpCBR + NAD<br />
 +
**[[3wlf]] – CpCBR + phenylethane diol<br />
 +
**[[3wnq]] – CpCBR (mutant) + hydroxyacetophenone<br />
*Carbonyl reductase binary complex with NADPH
*Carbonyl reductase binary complex with NADPH

Revision as of 09:46, 10 March 2015

Template:STRUCTURE 1cyd

Carbonyl reductase (CBR) catalyzes the reaction converting R-CHOH-R and NADP to R-CO-R’ and NADPH. CBR has wide substrate specificity oxidoreductase activity. CBR has similar properties to aldose reductase and aldehyde reductase.

3D structures of carbonyl reductase

Updated on 10-March-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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