4pfd
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of M. tuberculosis in complex with a cBT - non-covalent adduct== |
| - | + | <StructureSection load='4pfd' size='340' side='right' caption='[[4pfd]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4pfd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PFD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2R2:[4-(2-METHOXYETHYL)PIPERAZIN-1-YL][6-METHYL-7-NITRO-5-(TRIFLUOROMETHYL)-1,3-BENZOTHIAZOL-2-YL]METHANONE'>2R2</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p8h|4p8h]], [[4pfa|4pfa]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pfd OCA], [http://pdbe.org/4pfd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pfd RCSB], [http://www.ebi.ac.uk/pdbsum/4pfd PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/DPRE1_MYCTU DPRE1_MYCTU]] Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (DPR) to yield decaprenylphosphoryl 2-keto-ribose (DPX).<ref>PMID:16291675</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cole, S]] | ||
[[Category: Neres, J]] | [[Category: Neres, J]] | ||
| + | [[Category: Panda, M]] | ||
| + | [[Category: Covalent]] | ||
| + | [[Category: Dpre1]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
Revision as of 05:28, 22 October 2015
Crystal structure of M. tuberculosis in complex with a cBT - non-covalent adduct
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