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4yli

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'''Unreleased structure'''
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==CL-K1 trimer==
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<StructureSection load='4yli' size='340' side='right' caption='[[4yli]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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The entry 4yli is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4yli]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YLI FirstGlance]. <br>
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Authors: Wallis, R., Girija, U.V., Gingras, A.R., Moody, P.C.E., Marshall, J.E.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yli RCSB], [http://www.ebi.ac.uk/pdbsum/4yli PDBsum]</span></td></tr>
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Description: CL-K1 trimer
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</table>
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[[Category: Unreleased Structures]]
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== Disease ==
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[[Category: Girija, U.V]]
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[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Craniofacial-ulnar-renal syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Marshall, J.E]]
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== Function ==
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[[Category: Gingras, A.R]]
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[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity).
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[[Category: Moody, P.C.E]]
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__TOC__
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</StructureSection>
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[[Category: Gingras, A R]]
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[[Category: Girija, U V]]
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[[Category: Marshall, J E]]
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[[Category: Moody, P C.E]]
[[Category: Wallis, R]]
[[Category: Wallis, R]]
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[[Category: C-type carbohydrate-recognition domain]]
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[[Category: C-type lectin]]
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[[Category: Collectin]]
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[[Category: Sugar binding protein]]

Revision as of 11:19, 8 April 2015

CL-K1 trimer

4yli, resolution 2.45Å

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