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Cytochrome P450
From Proteopedia
(Difference between revisions)
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**[[4ejh]], [[4eji]] - hP4502A13 + pyridine derivative<BR /> | **[[4ejh]], [[4eji]] - hP4502A13 + pyridine derivative<BR /> | ||
**[[2p85]] – hP4502A13 (mutant)+indole<br /> | **[[2p85]] – hP4502A13 (mutant)+indole<br /> | ||
| - | **[[3tk3]] - hP4502B4 (mutant) + imidazole derivative<br /> | ||
| - | **[[4jlt]] - hP4502B4 (mutant) + drug<br /> | ||
**[[3ibd]] – hP4502B6 (mutant)+4-(4-chlorophenyl)imidazole<br /> | **[[3ibd]] – hP4502B6 (mutant)+4-(4-chlorophenyl)imidazole<br /> | ||
**[[3ua5]] – hP4502B6 (mutant) + amlodipine<br /> | **[[3ua5]] – hP4502B6 (mutant) + amlodipine<br /> | ||
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**[[2bdm]] – rP4502B4 – rabbit<br /> | **[[2bdm]] – rP4502B4 – rabbit<br /> | ||
**[[1po5]], [[3mvr]], [[3r1a]], [[3r1b]] - rP4502B4 (mutant)<br /> | **[[1po5]], [[3mvr]], [[3r1a]], [[3r1b]] - rP4502B4 (mutant)<br /> | ||
| - | **[[1suo]],[[3g5n]], [[3g93]], [[2q6n]] - rP4502B4 (mutant)+imidazole derivative<br /> | + | **[[1suo]],[[3g5n]], [[3g93]], [[2q6n]], [[3tk3]] - rP4502B4 (mutant)+imidazole derivative<br /> |
**[[4mgj]] - rP4502B4 (mutant)+ thiol derivative<br /> | **[[4mgj]] - rP4502B4 (mutant)+ thiol derivative<br /> | ||
**[[3kw4]], [[3me6]], [[3tmz]], [[4h1n]] - rP4502B4 (mutant)+anti-platelet drug<br /> | **[[3kw4]], [[3me6]], [[3tmz]], [[4h1n]] - rP4502B4 (mutant)+anti-platelet drug<br /> | ||
| + | **[[4jlt]] - rP4502B4 (mutant) + anti-depressant drug<br /> | ||
**[[3uas]] - rP4502B4 (mutant)+ inactivator<br /> | **[[3uas]] - rP4502B4 (mutant)+ inactivator<br /> | ||
**[[1dt6]] - rP4502C5 (mutant)<br /> | **[[1dt6]] - rP4502C5 (mutant)<br /> | ||
Revision as of 06:05, 14 May 2015
Cytochrome P450 (P450) catalyzes the oxidation of organic substances like lipids. catalyzes the oxidation of organic substances like lipids. The P450 contains a heme cofactor. The protein is numbered by its gene. For details on the human P45019 family see Aromatase.
- P450cam, also known as camphor 5-monooxygenase, catalyzes the hydroxylation of camphor.
- P450nor is a Nitric Oxide Reductase P450.
- P450epoK converts epothilone D to epothilone B.
- P450cin monooxygenates 1,8-cineole which is similar to camphor.
- Bifunctional P450/NADPH P450 reductase (P450 BM3) is a fatty acid monooxygenase.
Additional details in Drug Metabolism by CYP450 Enzymes.
3D Structures of Cytochrome P450
Updated on 14-May-2015
