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Methylcitrate synthase

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{{STRUCTURE_3tqg| PDB=3tqg | SIZE=400| SCENE= |right|CAPTION=Methylcitrate synthase dimer [[3tqg]] }}
{{STRUCTURE_3tqg| PDB=3tqg | SIZE=400| SCENE= |right|CAPTION=Methylcitrate synthase dimer [[3tqg]] }}
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'''Methylcitrate synthase''' (MCS) participates in propanoate metabolism. It catalyzes the conversion of acyl to alkyl group in the reaction which converts propanoyl-CoA and oxaloacetate to 2-hydroxybutane-1,2,3-tricarboxylate and CoA.
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'''Methylcitrate synthase''' (MCS) participates in propanoate metabolism. It catalyzes the conversion of acyl to alkyl group in the reaction which converts propanoyl-CoA and oxaloacetate to 2-hydroxybutane-1,2,3-tricarboxylate and CoA<ref>PMID:10482501</ref>.
See also [[Citrate Synthase]].
See also [[Citrate Synthase]].
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[[3tqg]] – MCS – ''Coxiella burnetii''
[[3tqg]] – MCS – ''Coxiella burnetii''
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:53, 25 April 2016

Template:STRUCTURE 3tqg

Methylcitrate synthase (MCS) participates in propanoate metabolism. It catalyzes the conversion of acyl to alkyl group in the reaction which converts propanoyl-CoA and oxaloacetate to 2-hydroxybutane-1,2,3-tricarboxylate and CoA[1].

See also Citrate Synthase.

3D structures of methylcitrate synthase

3hwk – MCS – Mycobacterium tuberculosis
3o8j – MCS – Salmonella enterica
3tqg – MCS – Coxiella burnetii

References

  1. Horswill AR, Escalante-Semerena JC. Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle. J Bacteriol. 1999 Sep;181(18):5615-23. PMID:10482501

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