2n0y
From Proteopedia
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| - | ''' | + | ==NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH== |
| - | + | <StructureSection load='2n0y' size='340' side='right' caption='[[2n0y]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2n0y]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N0Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N0Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2m14|2m14]], [[2lox|2lox]], [[1y5o|1y5o]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n0y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2n0y RCSB], [http://www.ebi.ac.uk/pdbsum/2n0y PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[Category: Chabot, P | + | [[http://www.uniprot.org/uniprot/TFB1_YEAST TFB1_YEAST]] Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.<ref>PMID:7961739</ref> <ref>PMID:8631896</ref> [[http://www.uniprot.org/uniprot/NSS_RVFVZ NSS_RVFVZ]] Inhibits host general transcription by inhibiting host basal transcription factor TFIIH.<ref>PMID:21543505</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chabot, P R]] | ||
[[Category: Cyr, N]] | [[Category: Cyr, N]] | ||
| - | [[Category: | + | [[Category: Fuente, C de la]] |
| - | + | ||
[[Category: Guendel, I]] | [[Category: Guendel, I]] | ||
| + | [[Category: Kehn-Hall, K]] | ||
[[Category: Lecoq, L]] | [[Category: Lecoq, L]] | ||
| - | [[Category: Omichinski, J | + | [[Category: Omichinski, J G]] |
| + | [[Category: Drug target]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Transcription-viral protein complex]] | ||
| + | [[Category: Viral protein-transcription complex]] | ||
| + | [[Category: Virulence]] | ||
| + | [[Category: Virus-host interface]] | ||
Revision as of 12:50, 22 April 2015
NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH
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