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EspG PE-PPE excretion is done through the ESX secretion pathway.
EspG PE-PPE excretion is done through the ESX secretion pathway.
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[[Image:EspG_PPE-PE_secretion.fw.png]]
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[[Image:EspG_PPE-PE_secretion.fw.png|350 px|left|thumb|specificity]]
=== Binding ===
=== Binding ===

Revision as of 12:30, 31 March 2015

Binding Specificity of EspG Proteins to PE-PPE Proteins in mycobacterium tuberculosis

Here shows PE25-PPE41 ligand bound to EspG5 protein. Resolution 2.60Å

Drag the structure with the mouse to rotate




References

  1. Ekiert DC, Cox JS. Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14758-63. doi:, 10.1073/pnas.1409345111. Epub 2014 Oct 1. PMID:25275011 doi:http://dx.doi.org/10.1073/pnas.1409345111
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