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4pzf

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==Berberine bridge enzyme G164A variant, a reticuline dehydrogenase==
==Berberine bridge enzyme G164A variant, a reticuline dehydrogenase==
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<StructureSection load='4pzf' size='340' side='right' caption='[[4pzf]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4pzf' size='340' side='right'caption='[[4pzf]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pzf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/California_poppy California poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PZF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pzf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PZF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pve|4pve]], [[4pvh|4pvh]], [[4pvj|4pvj]], [[4pvk|4pvk]], [[4pwb|4pwb]], [[4pwc|4pwc]], [[3d2h|3d2h]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pzf OCA], [https://pdbe.org/4pzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pzf RCSB], [https://www.ebi.ac.uk/pdbsum/4pzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pzf ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pzf RCSB], [http://www.ebi.ac.uk/pdbsum/4pzf PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA]] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
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[https://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4pzf" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Reticuline oxidase|Reticuline oxidase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: California poppy]]
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[[Category: Eschscholzia californica]]
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[[Category: Reticuline oxidase]]
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[[Category: Large Structures]]
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[[Category: Macheroux, P]]
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[[Category: Macheroux P]]
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[[Category: Steiner, B]]
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[[Category: Steiner B]]
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[[Category: Wallner, S]]
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[[Category: Wallner S]]
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[[Category: Zafred, D]]
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[[Category: Zafred D]]
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[[Category: Berberine bridge-forming enzyme]]
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[[Category: Bi-covalent flavinylation]]
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[[Category: Flavoprotein]]
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[[Category: Oxidoreductase]]
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[[Category: Tetrahydroprotoberberine synthase]]
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Revision as of 07:38, 8 February 2023

Berberine bridge enzyme G164A variant, a reticuline dehydrogenase

PDB ID 4pzf

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