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Exonuclease
From Proteopedia
(Difference between revisions)
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| - | + | <StructureSection load='1fxx' size='350' side='right' scene='' caption='E. coli exonuclease I complex with phosphate, glycerol and Mg+2 ion (PDB code [[1fxx]]) '> | |
| - | '''Exonucleases''' (ExN) cleave nucleotides at the end of a polynucleotide chain. In E. coli there are ExN I to VIII.<br /> | + | |
| + | '''Exonucleases''' (ExN) cleave nucleotides at the end of a polynucleotide chain<ref>PMID:8747466</ref>. In ''E. coli'' there are ExN I to VIII.<br /> | ||
* '''ExN-I''' cleaves single-stranded DNA.<br /> | * '''ExN-I''' cleaves single-stranded DNA.<br /> | ||
* '''ExN-II''' is associated with DNA polymerase.<br /> | * '''ExN-II''' is associated with DNA polymerase.<br /> | ||
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* '''ExN-VIII''' requires a free 5’ OH group for reacting.<br /> | * '''ExN-VIII''' requires a free 5’ OH group for reacting.<br /> | ||
* '''ExN''' were found in human and yeast as well. | * '''ExN''' were found in human and yeast as well. | ||
| + | </StructureSection> | ||
== 3D Structures of exonuclease == | == 3D Structures of exonuclease == | ||
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}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 18:11, 20 January 2016
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3D Structures of exonuclease
Updated on 20-January-2016
References
- ↑ Athappilly FK, Hendrickson WA. Structure of the biotinyl domain of acetyl-coenzyme A carboxylase determined by MAD phasing. Structure. 1995 Dec 15;3(12):1407-19. PMID:8747466
