4xes

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'''Unreleased structure'''
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==Structure of active-like neurotensin receptor==
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<StructureSection load='4xes' size='340' side='right' caption='[[4xes]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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The entry 4xes is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4xes]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XES OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XES FirstGlance]. <br>
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Authors: Krumm, B.E., White, J.F., Shah, P., Grisshammer, R.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xee|4xee]]</td></tr>
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Description: Structure of active-like neurotensin receptor
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xes FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xes OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xes RCSB], [http://www.ebi.ac.uk/pdbsum/4xes PDBsum]</span></td></tr>
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[[Category: Shah, P]]
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</table>
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[[Category: Krumm, B.E]]
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== Function ==
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[[http://www.uniprot.org/uniprot/NTR1_RAT NTR1_RAT]] Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. [[http://www.uniprot.org/uniprot/NEUT_RAT NEUT_RAT]] Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
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__TOC__
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</StructureSection>
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[[Category: Lysozyme]]
[[Category: Grisshammer, R]]
[[Category: Grisshammer, R]]
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[[Category: White, J.F]]
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[[Category: Krumm, B E]]
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[[Category: Shah, P]]
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[[Category: White, J F]]
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[[Category: G protein-coupled receptor]]
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[[Category: Gpcr]]
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[[Category: Hydrolase]]
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[[Category: Membrane protein]]
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[[Category: Neurotensin receptor]]
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[[Category: Ntsr1]]
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[[Category: Signaling protein]]

Revision as of 14:50, 29 July 2015

Structure of active-like neurotensin receptor

4xes, resolution 2.60Å

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