2rf3
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
|PDB= 2rf3 |SIZE=350|CAPTION= <scene name='initialview01'>2rf3</scene>, resolution 1.75Å | |PDB= 2rf3 |SIZE=350|CAPTION= <scene name='initialview01'>2rf3</scene>, resolution 1.75Å | ||
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+B+308'>AC1</scene> and <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+309'>AC2</scene> | |SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+B+308'>AC1</scene> and <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+309'>AC2</scene> | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=TCY:(2R,3AS,4AR,5AR,5BS)-2-(6-AMINO-9H-PURIN-9-YL)-3A-HYDROXYHEXAHYDROCYCLOPROPA[4,5]CYCLOPENTA[1,2-B]FURAN-5A(4H)-YL+DIHYDROGEN+PHOSPHATE'>TCY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rf3 OCA], [http://www.ebi.ac.uk/pdbsum/2rf3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rf3 RCSB]</span> | ||
}} | }} | ||
| Line 27: | Line 30: | ||
[[Category: Pallan, P S.]] | [[Category: Pallan, P S.]] | ||
[[Category: Wawrzak, Z.]] | [[Category: Wawrzak, Z.]] | ||
| - | [[Category: SPM]] | ||
| - | [[Category: ZN]] | ||
[[Category: conformationally constrained dna analog]] | [[Category: conformationally constrained dna analog]] | ||
[[Category: dna duplex]] | [[Category: dna duplex]] | ||
| Line 34: | Line 35: | ||
[[Category: x-ray crystal structure]] | [[Category: x-ray crystal structure]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:59:39 2008'' |
Revision as of 01:59, 31 March 2008
| |||||||
| , resolution 1.75Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | and | ||||||
| Ligands: | , , , , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles
Overview
The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.
About this Structure
2RF3 is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:18253536
Page seeded by OCA on Mon Mar 31 04:59:39 2008
