2rfi
From Proteopedia
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|PDB= 2rfi |SIZE=350|CAPTION= <scene name='initialview01'>2rfi</scene>, resolution 1.59Å | |PDB= 2rfi |SIZE=350|CAPTION= <scene name='initialview01'>2rfi</scene>, resolution 1.59Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span> |
|GENE= EHMT1, EUHMTASE1, KIAA1876 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= EHMT1, EUHMTASE1, KIAA1876 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2igq|2IGQ]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfi OCA], [http://www.ebi.ac.uk/pdbsum/2rfi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rfi RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide''' | '''Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Chromosome 9q subtelomeric deletion syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607001 607001]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
[[Category: Wu, H.]] | [[Category: Wu, H.]] | ||
| - | [[Category: SAH]] | ||
| - | [[Category: ZN]] | ||
[[Category: acetylation]] | [[Category: acetylation]] | ||
[[Category: alternative splicing]] | [[Category: alternative splicing]] | ||
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[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:59:50 2008'' |
Revision as of 01:59, 31 March 2008
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| , resolution 1.59Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | EHMT1, EUHMTASE1, KIAA1876 (Homo sapiens) | ||||||
| Activity: | Histone-lysine N-methyltransferase, with EC number 2.1.1.43 | ||||||
| Related: | 2IGQ
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide
About this Structure
2RFI is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:59:50 2008
Categories: Histone-lysine N-methyltransferase | Homo sapiens | Protein complex | Arrowsmith, C H. | Bochkarev, A. | Edwards, A M. | Loppnau, P. | Min, J. | Plotnikov, A N. | SGC, Structural Genomics Consortium. | Sundstrom, M. | Weigelt, J. | Wu, H. | Acetylation | Alternative splicing | Ank repeat | Chromatin regulator | Chromosomal protein | Dna damage | Dna repair | Dna-binding | Euchromatic histone methyltransferase 1 | Methylation | Nucleosome core | Nucleus | Phosphorylation | Polymorphism | S-adenosyl-l-methionine | Sgc | Structural genomic | Structural genomics consortium
