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4wy6

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==Crystal structure of human BACE-1 bound to Compound 36==
==Crystal structure of human BACE-1 bound to Compound 36==
<StructureSection load='4wy6' size='340' side='right' caption='[[4wy6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4wy6' size='340' side='right' caption='[[4wy6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VP:(4AR,6R,8AS)-8A-(2,4-DIFLUOROPHENYL)-6-(FLUOROMETHYL)-4,4A,5,6,8,8A-HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE'>3VP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VP:(4AR,6R,8AS)-8A-(2,4-DIFLUOROPHENYL)-6-(FLUOROMETHYL)-4,4A,5,6,8,8A-HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE'>3VP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wy6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wy6 RCSB], [http://www.ebi.ac.uk/pdbsum/4wy6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wy6 OCA], [http://pdbe.org/4wy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wy6 RCSB], [http://www.ebi.ac.uk/pdbsum/4wy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wy6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4wy6" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==

Revision as of 00:16, 26 January 2017

Crystal structure of human BACE-1 bound to Compound 36

4wy6, resolution 2.10Å

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