4yvq
From Proteopedia
(Difference between revisions)
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- | ''' | + | ==The Non-canonical Tetratricopeptide-repeat (TPR) Domain of FLUORESCENT (FLU) Mediates Complex Formation with Glutamyl-tRNA Reductase== |
- | + | <StructureSection load='4yvq' size='340' side='right' caption='[[4yvq]], [[Resolution|resolution]] 2.40Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4yvq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YVQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YVQ FirstGlance]. <br> | |
- | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yvo|4yvo]]</td></tr> | |
- | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamyl-tRNA_reductase Glutamyl-tRNA reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.70 1.2.1.70] </span></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yvq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yvq RCSB], [http://www.ebi.ac.uk/pdbsum/4yvq PDBsum]</span></td></tr> | |
- | [[Category: | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/HEM11_ARATH HEM11_ARATH]] Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). Probably involved in the tetrapyrrole synthesis required for the chlorophyll biosynthesis.<ref>PMID:7908550</ref> <ref>PMID:12139011</ref> [[http://www.uniprot.org/uniprot/FLU_ARATH FLU_ARATH]] Negative regulator of tetrapyrrole biosynthesis (including chlorophyll) in chloroplasts, probably via HEMA1 repression. Inhibits especially the magnesium ion Mg(2+) branch of tetrapyrrole biosynthesis, but independently of heme.<ref>PMID:11606728</ref> <ref>PMID:14508004</ref> <ref>PMID:15584960</ref> <ref>PMID:18182022</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Glutamyl-tRNA reductase]] | ||
[[Category: Liu, L]] | [[Category: Liu, L]] | ||
[[Category: Zhang, F]] | [[Category: Zhang, F]] | ||
[[Category: Zhang, M]] | [[Category: Zhang, M]] | ||
+ | [[Category: Chloroplast]] | ||
+ | [[Category: Protein-protein interaction]] | ||
+ | [[Category: Tpr]] |
Revision as of 14:11, 10 June 2015
The Non-canonical Tetratricopeptide-repeat (TPR) Domain of FLUORESCENT (FLU) Mediates Complex Formation with Glutamyl-tRNA Reductase
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