2uvm
From Proteopedia
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|PDB= 2uvm |SIZE=350|CAPTION= <scene name='initialview01'>2uvm</scene>, resolution 1.94Å | |PDB= 2uvm |SIZE=350|CAPTION= <scene name='initialview01'>2uvm</scene>, resolution 1.94Å | ||
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+A'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+A'>AC1</scene> | ||
- | |LIGAND= | + | |LIGAND= <scene name='pdbligand=GVF:BENZENE-1,2,3,4-TETRAYL+TETRAKIS[DIHYDROGEN+(PHOSPHATE)]'>GVF</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> |
- | |ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span> |
|GENE= | |GENE= | ||
+ | |DOMAIN= | ||
+ | |RELATEDENTRY= | ||
+ | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uvm OCA], [http://www.ebi.ac.uk/pdbsum/2uvm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2uvm RCSB]</span> | ||
}} | }} | ||
'''STRUCTURE OF PKBALPHA PH DOMAIN IN COMPLEX WITH A NOVEL INOSITOL HEADGROUP SURROGATE, BENZENE 1,2,3,4-TETRAKISPHOSPHATE''' | '''STRUCTURE OF PKBALPHA PH DOMAIN IN COMPLEX WITH A NOVEL INOSITOL HEADGROUP SURROGATE, BENZENE 1,2,3,4-TETRAKISPHOSPHATE''' | ||
- | |||
- | ==Disease== | ||
- | Known diseases associated with this structure: Breast cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164730 164730]], Colorectal cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164730 164730]], Neutrophil immunodeficiency syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602049 602049]], Ovarian cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164730 164730]], Schizophrenia, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164730 164730]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Safrany, S T.]] | [[Category: Safrany, S T.]] | ||
[[Category: Trussle, M N.]] | [[Category: Trussle, M N.]] | ||
- | [[Category: GVF]] | ||
- | [[Category: NA]] | ||
[[Category: apoptosis]] | [[Category: apoptosis]] | ||
[[Category: atp-binding]] | [[Category: atp-binding]] | ||
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[[Category: transport]] | [[Category: transport]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:05:07 2008'' |
Revision as of 02:05, 31 March 2008
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, resolution 1.94Å | |||||||
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Sites: | |||||||
Ligands: | , | ||||||
Activity: | Non-specific serine/threonine protein kinase, with EC number 2.7.11.1 | ||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
STRUCTURE OF PKBALPHA PH DOMAIN IN COMPLEX WITH A NOVEL INOSITOL HEADGROUP SURROGATE, BENZENE 1,2,3,4-TETRAKISPHOSPHATE
About this Structure
2UVM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:05:07 2008
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Single protein | Aalten, D M.F Van. | Komander, D. | Mills, S J. | Potter, B V.L. | Safrany, S T. | Trussle, M N. | Apoptosis | Atp-binding | Cancer | Carbohydrate metabolism | Cell signalling | Glucose metabolism | Glycogen biosynthesis | Glycogen metabolism | Inositol | Kinase | Nuclear protein | Nucleotide-binding | Ph domain | Phosphoinositide | Phosphorylation | Protein kinase b | Serine/threonine-protein kinase | Sugar transport | Transferase | Translation regulation | Transport