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Growth differentiation factor

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'''Growth differentiation factor''' (GDF) are proteins which function in development.<br />
'''Growth differentiation factor''' (GDF) are proteins which function in development.<br />
*'''GDF-2''' or '''bone morphogenetic protein 9''' maintains the response of cholinergic neurons to acetylcholine.<br />
*'''GDF-2''' or '''bone morphogenetic protein 9''' maintains the response of cholinergic neurons to acetylcholine.<br />
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*'''GDF-5''' is expressed in the central nervous system and is involved in the development of joints and skeleton.<br />
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*'''GDF-5''' is expressed in the central nervous system and is involved in the development of joints and skeleton<ref>PMID:23432680</ref>.<br />
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*'''GDF-8''' or '''myostatin''', controls the growth of muscle tissue. For more details see [[Group:MUZIC:Myostatin]].
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*'''GDF-8''' or '''myostatin''', controls the growth of muscle tissue<ref>PMID:10610713</ref>. For more details see [[Group:MUZIC:Myostatin]].
</StructureSection>
</StructureSection>
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**[[3sek]] – mGDF + follistatin-related protein <br />
**[[3sek]] – mGDF + follistatin-related protein <br />
}}
}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:05, 16 March 2016

Structure of growth differentiation factor GDF-5 (green) complex with bone morphogenetic receptor (pink) (PDB entry 3evs)

Drag the structure with the mouse to rotate

3D structures of growth differentiation factor

Updated on 16-March-2016

References

  1. ↑ Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73. PMID:23432680
  2. ↑ Ferrell RE, Conte V, Lawrence EC, Roth SM, Hagberg JM, Hurley BF. Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics. 1999 Dec 1;62(2):203-7. PMID:10610713 doi:http://dx.doi.org/10.1006/geno.1999.5984

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Michal Harel, Alexander Berchansky

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