NAD(P) transhydrogenase
From Proteopedia
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<StructureSection load='1u28' size='350' side='right' caption='Structure of PTH domains I (grey and green) and III (pink) complex with NAD and NADP (PDB entry [[1u28]])' scene=''> | <StructureSection load='1u28' size='350' side='right' caption='Structure of PTH domains I (grey and green) and III (pink) complex with NAD and NADP (PDB entry [[1u28]])' scene=''> | ||
| - | '''NAD(P) transhydrogenase''' (PTH) catalyzes the conversion of NADP and NADH to NADPH and NAD. The reaction is coupled with proton translocation across the cell membrane while the enzyme undergoes conformational change. PTH uses FAD as cofactor. PTH is composed of 3 domains.:<br /> | + | '''NAD(P) transhydrogenase''' (PTH) catalyzes the conversion of NADP and NADH to NADPH and NAD. See [[NAD]] and [[NAD(P)H]]. The reaction is coupled with proton translocation across the cell membrane while the enzyme undergoes conformational change. PTH uses FAD as cofactor. PTH is composed of 3 domains.:<br /> |
* Domain I binds NAD(+)/NADH.<br /> | * Domain I binds NAD(+)/NADH.<br /> | ||
* Domain II is a membrane-spanning domain.<br /> | * Domain II is a membrane-spanning domain.<br /> | ||
Revision as of 08:39, 16 February 2016
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3D structures of NAD(P) transhydrogenase
Updated on 16-February-2016
