4zi0

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m (Protected "4zi0" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region without a chelation to the metal ions in the active site==
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<StructureSection load='4zi0' size='340' side='right' caption='[[4zi0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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The entry 4zi0 is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4zi0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZI0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZI0 FirstGlance]. <br>
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Authors: Fudo, S., Yamamoto, N., Nukaga, M., Odagiri, T., Tashiro, M., Neya, S., Hoshino, T.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4P9:4-{(E)-[2-(4-CHLOROPHENYL)HYDRAZINYLIDENE]METHYL}BENZENE-1,2,3-TRIOL'>4P9</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yyl|4yyl]], [[4zhz|4zhz]]</td></tr>
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Description: Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region without a chelation to the metal ions in the active site
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zi0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zi0 RCSB], [http://www.ebi.ac.uk/pdbsum/4zi0 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PA_I34A1 PA_I34A1]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.
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__TOC__
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</StructureSection>
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[[Category: Fudo, S]]
[[Category: Hoshino, T]]
[[Category: Hoshino, T]]
[[Category: Neya, S]]
[[Category: Neya, S]]
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[[Category: Tashiro, M]]
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[[Category: Nukaga, M]]
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[[Category: Fudo, S]]
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[[Category: Odagiri, T]]
[[Category: Odagiri, T]]
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[[Category: Tashiro, M]]
[[Category: Yamamoto, N]]
[[Category: Yamamoto, N]]
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[[Category: Nukaga, M]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 12:27, 13 May 2015

Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region without a chelation to the metal ions in the active site

4zi0, resolution 1.80Å

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