Peptidyl-prolyl cis-trans isomerase

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**[[3k2c]] – PPIase – ''Encephalitozoon cuniculi''<BR />
**[[3k2c]] – PPIase – ''Encephalitozoon cuniculi''<BR />
 +
**[[1yw5]] – PPIase – ''Candida albicans''<BR />
 +
**[[2jv4]] – PPIase A WW domain – ''Emericella nidulans'' - NMR<BR />
 +
**[[2mc9]] – PPIase – rosy periwinkle - NMR<BR />
 +
**[[2wlw]] – PPIase CypA domain – ''Macaca mulatta'' <BR />
 +
**[[3oe2]] – PPIase – ''Pseudomonas syringae''<BR />
 +
**[[4s1e]], [[4s1j]] – PPIase (mutant) – ''Leishmania donovani''<BR />
-
*Pin1
+
*PPIase Pin1
**[[1pin]] – hPin1 – human<BR />
**[[1pin]] – hPin1 – human<BR />
**[[1nmv]] – hPin1 - NMR<BR />
**[[1nmv]] – hPin1 - NMR<BR />
**[[1zcn]], [[2zqs]], [[2zqt]], [[2zqu]], [[2zqv]], [[2zr4]], [[2zr5]], [[2zr6]] – hPin1 (mutant)<BR />
**[[1zcn]], [[2zqs]], [[2zqt]], [[2zqu]], [[2zqv]], [[2zr4]], [[2zr5]], [[2zr6]] – hPin1 (mutant)<BR />
-
**[[1i6c]], [[2kcf]], [[2kbu]] – hPin1 WW domain - NMR<BR />
+
**[[1i6c]], [[2kcf]], [[2kbu]], [[1eq3]], [[2m8i]], [[2m8j]] – hPin1 WW domain - NMR<BR />
-
**[[2f21]] – hPin1 WW domain (mutant)<BR />
+
**[[2f21]], [[1fjd]], [[2m9e]], [[2m9f]], [[2m9i]], [[2m9j]] – hPin1 WW domain (mutant)<BR />
**[[3ik8]] – hPin1 PPIase domain (mutant)<BR />
**[[3ik8]] – hPin1 PPIase domain (mutant)<BR />
-
**[[1nmw]] – hPin1 PPIase domain - NMR<BR />
+
**[[2rud]] – hPin1 PPIase domain (mutant) - NMR<BR />
 +
**[[1nmw]], [[2ruc]] – hPin1 PPIase domain - NMR<BR />
**[[1j6y]] – Pin1 – ''Arabidopsis thaliana'' - NMR<BR />
**[[1j6y]] – Pin1 – ''Arabidopsis thaliana'' - NMR<BR />
-
*Pin1 complexes
+
*PPIase Pin1 complexes
**[[1f8a]] – hPin1 + phosphoserine containing peptide<BR />
**[[1f8a]] – hPin1 + phosphoserine containing peptide<BR />
**[[1i8g]], [[1i8h]] – hPin1 WW domain + phosphothreoniine containing peptide - NMR<BR />
**[[1i8g]], [[1i8h]] – hPin1 WW domain + phosphothreoniine containing peptide - NMR<BR />
**[[2lb3]] – hPin1 WW domain + MAD homolog peptide - NMR<BR />
**[[2lb3]] – hPin1 WW domain + MAD homolog peptide - NMR<BR />
 +
**[[4gwt]], [[4gwv]] – hPin1 WW domain + small molecule<BR />
**[[2itk]] – hPin1 (mutant) + D-peptide<BR />
**[[2itk]] – hPin1 (mutant) + D-peptide<BR />
**[[2q5a]] – hPin1 (mutant) + L-peptide<BR />
**[[2q5a]] – hPin1 (mutant) + L-peptide<BR />
-
**[[3ikd]], [[3ikg]], [[3kac]], [[3jyj]], [[3i6c]] – hPin1 PPIase domain (mutant) + inhibitor<BR />
+
**[[3ikd]], [[3ikg]], [[3kac]], [[3jyj]], [[3i6c]], [[3tc5]] – hPin1 PPIase domain (mutant) + inhibitor<BR />
-
**[[3kab]], [[3kad]], [[3kaf]], [[3kag]], [[3kah]], [[3kai]], [[3kce]], [[3odk]], [[2xp3]], [[2xp4]], [[2xp5]], [[2xp6]], [[2xp7]], [[2xp8]], [[2xp9]], [[2xpa]], [[2xpb]], [[3oob]], [[3ntp]], [[3tcz]], [[3tdb]] – hPin1 (mutant) + inhibitor<BR />
+
**[[4tns]] – hPin1 PPIase domain (mutant) + retinoic acid<BR />
 +
**[[3kab]], [[3kad]], [[3kaf]], [[3kag]], [[3kah]], [[3kai]], [[3kce]], [[3odk]], [[2xp3]], [[2xp4]], [[2xp5]], [[2xp6]], [[2xp7]], [[2xp8]], [[2xp9]], [[2xpa]], [[2xpb]], [[3oob]], [[3ntp]], [[3tcz]], [[3tdb]], [[4qib]], [[4tyo]] – hPin1 (mutant) + inhibitor<BR />
 +
**[[4u84]], [[4u85]], [[4u86]] – hPin1 + inhibitor<BR />
 +
**[[3wh0]] – hPin1 (mutant) + crown ether<BR />
**[[3oob]] – hPin1 (mutant) + dexamethasone phosphate<BR />
**[[3oob]] – hPin1 (mutant) + dexamethasone phosphate<BR />
 +
**[[1c5f]] – Pin1 cyclophilin-like domain + cyclosporine A – Brugia malayi <BR />
-
*Mip
+
*PPIase Pin4
 +
 
 +
**[[3ui4]], [[3ui5]] – hPin4 <BR />
 +
**[[3ui6]] – hPin4 + dithiane diol <BR />
 +
 
 +
*PPIase Mip
**[[1fd9]] – LpMip – ''Legionella pneumophila''<BR />
**[[1fd9]] – LpMip – ''Legionella pneumophila''<BR />
 +
**[[2y78]] – BpMip <BR />
**[[2uz5]] – LpMip FKBP domain - NMR<BR />
**[[2uz5]] – LpMip FKBP domain - NMR<BR />
**[[2vcd]] – LpMip FKBP domain + rapamycin - NMR<BR />
**[[2vcd]] – LpMip FKBP domain + rapamycin - NMR<BR />
**[[1jvw]] – Mip – ''Trypanosoma cruzi''<BR />
**[[1jvw]] – Mip – ''Trypanosoma cruzi''<BR />
-
*SlyD
+
*PPIase SlyD
**[[2k8i]], [[2kfw]] – EcSlyD – ''Escherichia coli'' - NMR<BR />
**[[2k8i]], [[2kfw]] – EcSlyD – ''Escherichia coli'' - NMR<BR />
**[[2kr7]] – FKBP SlyD – NMR - ''Helicobacter pylori''<br />
**[[2kr7]] – FKBP SlyD – NMR - ''Helicobacter pylori''<br />
 +
**[[3cgm]], [[3cgn]] – TtSlyD – ''Themus thermophilus''<BR />
 +
**[[3luo]] – TtSlyD + peptide<BR />
 +
**[[4odk]] – TtSlyD + RNAse T1 peptide<BR />
 +
**[[4odl]], [[4odm]], [[4odn]], [[4odp]] – TtSlyD + RPS2 peptide<BR />
 +
**[[4odq]] – TtSlyD + RPS3 peptide<BR />
 +
**[[4odo]] – TtSlyD + FK506<BR />
-
*SlpA
+
*PPIase SlpA
**[[4dt4]] – EcSlpA <BR />
**[[4dt4]] – EcSlpA <BR />
 +
 +
*PPIase 3 see [[Cyclophilin]]-3<br />
 +
*PPIase 5 see [[Cyclophilin]]-5<br />
 +
*PPIase 38 see [[Cyclophilin]]-38<br />
 +
*PPIase A see [[Cyclophilin]]-A<br />
 +
*PPIase B see [[Cyclophilin]]-B<br />
 +
*PPIase C see [[Cyclophilin]]-C<br />
 +
*PPIase D see [[Cyclophilin]]-D<br />
 +
*PPIase E see [[Cyclophilin]]-E<br />
 +
*PPIase F see [[Cyclophilin]]-F<br />
 +
*PPIase G see [[Cyclophilin]]-G<br />
 +
*PPIase FKBP see [[FK506 binding protein]]<br />
 +

Revision as of 10:07, 10 May 2015

Human PPIase complex with phosphoserine containing peptide (magenta) (PDB code 1f8a).

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3D Structures of peptidyl-prolyl cis-trans isomerase

Updated on 10-May-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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