This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4zdr
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal structure of 14-3-3[zeta]-LKB1 fusion protein== |
| - | + | <StructureSection load='4zdr' size='340' side='right' caption='[[4zdr]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4zdr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZDR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZDR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TME:PROPANE'>TME</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zdr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zdr RCSB], [http://www.ebi.ac.uk/pdbsum/4zdr PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/1433Z_HUMAN 1433Z_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:9360956</ref> <ref>PMID:14578935</ref> <ref>PMID:15071501</ref> <ref>PMID:15644438</ref> <ref>PMID:16376338</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Ding, S]] | [[Category: Ding, S]] | ||
| - | [[Category: Shi, Z]] | + | [[Category: Shi, Z B]] |
| + | [[Category: Chimeric protein]] | ||
| + | [[Category: Protein binding]] | ||
| + | [[Category: Regulatory protein]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Tumor suppressor]] | ||
Revision as of 11:21, 9 September 2015
Crystal structure of 14-3-3[zeta]-LKB1 fusion protein
| |||||||||||
