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4q8n
From Proteopedia
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==tRNA-Guanine Transglycosylase (TGT) Mutant V262C Apo Structure== | ==tRNA-Guanine Transglycosylase (TGT) Mutant V262C Apo Structure== | ||
<StructureSection load='4q8n' size='340' side='right' caption='[[4q8n]], [[Resolution|resolution]] 1.45Å' scene=''> | <StructureSection load='4q8n' size='340' side='right' caption='[[4q8n]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pud|1pud]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pud|1pud]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA-guanine(34)_transglycosylase tRNA-guanine(34) transglycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA-guanine(34)_transglycosylase tRNA-guanine(34) transglycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q8n RCSB], [http://www.ebi.ac.uk/pdbsum/4q8n PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q8n OCA], [http://pdbe.org/4q8n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q8n RCSB], [http://www.ebi.ac.uk/pdbsum/4q8n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q8n ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | [[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | ||
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| + | ==See Also== | ||
| + | *[[TRNA-guanine transglycosylase|TRNA-guanine transglycosylase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 17:34, 9 March 2017
tRNA-Guanine Transglycosylase (TGT) Mutant V262C Apo Structure
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