366d

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|PDB= 366d |SIZE=350|CAPTION= <scene name='initialview01'>366d</scene>, resolution 1.30&Aring;
|PDB= 366d |SIZE=350|CAPTION= <scene name='initialview01'>366d</scene>, resolution 1.30&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=DA6:6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA6</scene>
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|LIGAND= <scene name='pdbligand=BRU:5-BROMO-2&#39;-DEOXYURIDINE-5&#39;-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DA6:6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA6</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=366d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=366d OCA], [http://www.ebi.ac.uk/pdbsum/366d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=366d RCSB]</span>
}}
}}
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[[Category: Thorpe, J H.]]
[[Category: Thorpe, J H.]]
[[Category: Todd, A K.]]
[[Category: Todd, A K.]]
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[[Category: DA6]]
 
[[Category: dna]]
[[Category: dna]]
[[Category: drug intercalation]]
[[Category: drug intercalation]]
[[Category: major groove binding]]
[[Category: major groove binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:55:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:51 2008''

Revision as of 02:21, 31 March 2008


PDB ID 366d

Drag the structure with the mouse to rotate
, resolution 1.30Å
Ligands: , , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX


About this Structure

366D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960

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