4zjd
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Small heat shock protein AgsA from Salmonella typhimurium: Truncations at N- and C- termini== | |
| + | <StructureSection load='4zjd' size='340' side='right' caption='[[4zjd]], [[Resolution|resolution]] 7.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4zjd]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZJD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZJD FirstGlance]. <br> | ||
| + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zj9|4zj9]], [[4zja|4zja]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zjd OCA], [http://pdbe.org/4zjd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zjd RCSB], [http://www.ebi.ac.uk/pdbsum/4zjd PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Small heat shock proteins are ubiquitous molecular chaperones that form the first line of defence against the detrimental effects of cellular stress. Under conditions of stress they undergo drastic conformational rearrangements in order to bind to misfolded substrate proteins and prevent cellular protein aggregation. Owing to the dynamic nature of small heat shock protein oligomers, elucidating the structural basis of chaperone action and oligomerization still remains a challenge. In order to understand the organization of sHSP oligomers, we have determined crystal structures of a small heat shock protein from Salmonella typhimurium in a dimeric form and two higher oligomeric forms: an 18-mer and a 24-mer. Though the core dimer structure is conserved in all the forms, structural heterogeneity arises due to variation in the terminal regions. | ||
| - | + | Multiple oligomeric structures of a bacterial small heat shock protein.,Mani N, Bhandari S, Moreno R, Hu L, Prasad BV, Suguna K Sci Rep. 2016 Apr 7;6:24019. doi: 10.1038/srep24019. PMID:27053150<ref>PMID:27053150</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 4zjd" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Mani, N]] | [[Category: Mani, N]] | ||
[[Category: Suguna, K]] | [[Category: Suguna, K]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Crystallin]] | ||
| + | [[Category: Oligomer]] | ||
| + | [[Category: Small heat shock protein]] | ||
Revision as of 18:39, 12 May 2016
Small heat shock protein AgsA from Salmonella typhimurium: Truncations at N- and C- termini
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