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3b7o

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|PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60&Aring;
|PDB= 3b7o |SIZE=350|CAPTION= <scene name='initialview01'>3b7o</scene>, resolution 1.60&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=MLT:MALATE ION'>MLT</scene>
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|LIGAND= <scene name='pdbligand=MLT:MALATE+ION'>MLT</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
|GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= PTPN11, PTP2C, SHPTP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=
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|RELATEDENTRY=[[2shp|2SHP]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7o OCA], [http://www.ebi.ac.uk/pdbsum/3b7o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b7o RCSB]</span>
}}
}}
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site'''
'''Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site'''
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==Disease==
 
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Known diseases associated with this structure: Leopard syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Leukemia, juvenile myelomonocytic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]], Noonan syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176876 176876]]
 
==About this Structure==
==About this Structure==
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[[Category: Ugochukwu, E.]]
[[Category: Ugochukwu, E.]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
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[[Category: MLT]]
 
[[Category: alternative splicing]]
[[Category: alternative splicing]]
[[Category: cytoplasm]]
[[Category: cytoplasm]]
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[[Category: tyrosine phosphatase]]
[[Category: tyrosine phosphatase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:56:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:23:51 2008''

Revision as of 02:23, 31 March 2008

Image:3b7o.gif


PDB ID 3b7o

Drag the structure with the mouse to rotate
, resolution 1.60Å
Ligands:
Gene: PTPN11, PTP2C, SHPTP2 (Homo sapiens)
Activity: Protein-tyrosine-phosphatase, with EC number 3.1.3.48
Related: 2SHP


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site


About this Structure

3B7O is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 05:23:51 2008

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