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5bpw

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'''Unreleased structure'''
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==Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain==
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<StructureSection load='5bpw' size='340' side='right' caption='[[5bpw]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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The entry 5bpw is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5bpw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BPW FirstGlance]. <br>
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Authors: Kulkarni, K., Yang, J., Zhang, Z., Barford, D.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bpw RCSB], [http://www.ebi.ac.uk/pdbsum/5bpw PDBsum]</span></td></tr>
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</table>
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Description: Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain
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== Function ==
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[[Category: Unreleased Structures]]
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[[http://www.uniprot.org/uniprot/APC4_HUMAN APC4_HUMAN]] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref>
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[[Category: Zhang, Z]]
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== References ==
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[[Category: Yang, J]]
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<references/>
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[[Category: Kulkarni, K]]
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__TOC__
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</StructureSection>
[[Category: Barford, D]]
[[Category: Barford, D]]
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[[Category: Kulkarni, K]]
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[[Category: Yang, J]]
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[[Category: Zhang, Z]]
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[[Category: Anaphase promoting complex]]
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[[Category: Apc/c]]
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[[Category: Apc4]]
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[[Category: Cell cycle]]

Revision as of 12:34, 2 September 2015

Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain

5bpw, resolution 3.40Å

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