5a56
From Proteopedia
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| - | ''' | + | ==The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with 1-O-methyl-T-antigen== |
| - | + | <StructureSection load='5a56' size='340' side='right' caption='[[5a56]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5a56]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A56 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MGC:ALPHA-METHYL-N-ACETYL-D-GALACTOSAMINE'>MGC</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a55|5a55]], [[5a57|5a57]], [[5a58|5a58]], [[5a59|5a59]], [[5a5a|5a5a]]</td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-alpha-N-acetylgalactosaminidase Endo-alpha-N-acetylgalactosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.97 3.2.1.97] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a56 RCSB], [http://www.ebi.ac.uk/pdbsum/5a56 PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Boraston, A | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/GH101_STRPN GH101_STRPN]] Is involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins. Is representative of a broadly important class of virulence factors (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Endo-alpha-N-acetylgalactosaminidase]] | ||
| + | [[Category: Boraston, A B]] | ||
[[Category: Deng, L]] | [[Category: Deng, L]] | ||
| - | [[Category: | + | [[Category: Gregg, K J]] |
| + | [[Category: Suits, M D.L]] | ||
| + | [[Category: Vocadlo, D J]] | ||
| + | [[Category: Endo-beta-n-acetylgalactosaminidase]] | ||
| + | [[Category: Gh101]] | ||
| + | [[Category: Glycoside hydrolase family 101]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mucin degradation]] | ||
| + | [[Category: T-antigen]] | ||
Revision as of 12:32, 2 September 2015
The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with 1-O-methyl-T-antigen
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