5a58
From Proteopedia
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| - | ''' | + | ==The structure of GH101 D764N mutant from Streptococcus pneumoniae TIGR4 in complex with serinyl T-antigen== |
| - | + | <StructureSection load='5a58' size='340' side='right' caption='[[5a58]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5a58]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A58 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A58 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a55|5a55]], [[5a56|5a56]], [[5a57|5a57]], [[5a59|5a59]], [[5a5a|5a5a]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a58 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a58 RCSB], [http://www.ebi.ac.uk/pdbsum/5a58 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/GH101_STRPN GH101_STRPN]] Is involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins. Is representative of a broadly important class of virulence factors (By similarity). |
| - | [[Category: Boraston, A | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Boraston, A B]] | ||
[[Category: Deng, L]] | [[Category: Deng, L]] | ||
| - | [[Category: | + | [[Category: Gregg, K J]] |
| + | [[Category: Suits, M D.L]] | ||
| + | [[Category: Vocadlo, D J]] | ||
| + | [[Category: Endo-beta-n-acetylgalactosaminidase]] | ||
| + | [[Category: Gh101]] | ||
| + | [[Category: Glycoside hydrolase family 101]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mucin degradation]] | ||
| + | [[Category: T-antigen]] | ||
Revision as of 12:32, 2 September 2015
The structure of GH101 D764N mutant from Streptococcus pneumoniae TIGR4 in complex with serinyl T-antigen
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