This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2n3o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 2n3o is ON HOLD until Paper Publication
+
==Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA==
-
 
+
<StructureSection load='2n3o' size='340' side='right' caption='[[2n3o]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-
Authors: Maris, C., Jayne, S.F., Damberger, F.F., Ravindranathan, S., Allain, F.H.-T.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2n3o]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N3O FirstGlance]. <br>
-
Description: Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ad9|2ad9]], [[1sjq|1sjq]]</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n3o OCA], [http://pdbe.org/2n3o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n3o RCSB], [http://www.ebi.ac.uk/pdbsum/2n3o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n3o ProSAT]</span></td></tr>
-
[[Category: Jayne, S.F]]
+
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/PTBP1_HUMAN PTBP1_HUMAN]] Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.<ref>PMID:11003644</ref> <ref>PMID:15009664</ref> <ref>PMID:16260624</ref> <ref>PMID:21518792</ref> <ref>PMID:16179478</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Allain, F H.T]]
 +
[[Category: Damberger, F F]]
 +
[[Category: Jayne, S F]]
 +
[[Category: Maris, C]]
[[Category: Ravindranathan, S]]
[[Category: Ravindranathan, S]]
-
[[Category: Allain, F.H.-T]]
+
[[Category: C-terminal helix formation]]
-
[[Category: Damberger, F.F]]
+
[[Category: Ire]]
-
[[Category: Maris, C]]
+
[[Category: Polypyirimine tract binding protein]]
 +
[[Category: Ptb]]
 +
[[Category: Rna binding protein-rna complex]]

Revision as of 16:16, 10 August 2016

Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2n3o"
Personal tools