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5a68
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| - | ''' | + | ==Crystal structure of the AtTTM3 product complex with two orthophosphates and manganese ions (form B)== |
| - | + | <StructureSection load='5a68' size='340' side='right' caption='[[5a68]], [[Resolution|resolution]] 1.67Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5a68]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A68 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a5y|5a5y]], [[5a60|5a60]], [[5a61|5a61]], [[5a64|5a64]], [[5a65|5a65]], [[5a66|5a66]], [[5a67|5a67]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a68 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a68 RCSB], [http://www.ebi.ac.uk/pdbsum/5a68 PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TTM3_ARATH TTM3_ARATH]] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), however it does not display significant activity towards long-chain polyphosphates. The existence of PPPi in living cells is still unclear, and PPPase activity might be the ancestral function of CYTH domain. It also has gamma-phosphatase activity on NTP substrates, but no adenylate cyclase or RNA triphosphatase activity.<ref>PMID:24004165</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hothorn, M]] | ||
[[Category: Martinez, J]] | [[Category: Martinez, J]] | ||
[[Category: Truffault, V]] | [[Category: Truffault, V]] | ||
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Inorganic polyphosphate]] | ||
| + | [[Category: Triphosphate tunnel metalloenzyme]] | ||
| + | [[Category: Tripolyphosphate]] | ||
Revision as of 20:18, 5 August 2015
Crystal structure of the AtTTM3 product complex with two orthophosphates and manganese ions (form B)
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