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5cfb
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine== |
| - | + | <StructureSection load='5cfb' size='340' side='right' caption='[[5cfb]], [[Resolution|resolution]] 3.04Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5cfb]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CFB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SY9:STRYCHNINE'>SY9</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cfb OCA], [http://pdbe.org/5cfb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cfb RCSB], [http://www.ebi.ac.uk/pdbsum/5cfb PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/GLRA3_HUMAN GLRA3_HUMAN]] The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Chen, H]] | [[Category: Chen, H]] | ||
| - | [[Category: Shaffer, P | + | [[Category: Huang, X]] |
| + | [[Category: Shaffer, P L]] | ||
| + | [[Category: Cys-loop receptor]] | ||
| + | [[Category: Ligand-gated ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Neurotransmitter receptor]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 14:43, 30 September 2015
Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine
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