5tln

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|PDB= 5tln |SIZE=350|CAPTION= <scene name='initialview01'>5tln</scene>, resolution 2.3&Aring;
|PDB= 5tln |SIZE=350|CAPTION= <scene name='initialview01'>5tln</scene>, resolution 2.3&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=BAN:HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE'>BAN</scene>
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|LIGAND= <scene name='pdbligand=BAN:HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE'>BAN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tln OCA], [http://www.ebi.ac.uk/pdbsum/5tln PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=5tln RCSB]</span>
}}
}}
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[[Category: Holmes, M A.]]
[[Category: Holmes, M A.]]
[[Category: Matthews, B W.]]
[[Category: Matthews, B W.]]
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[[Category: BAN]]
 
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[[Category: CA]]
 
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[[Category: ZN]]
 
[[Category: hydrolase (metalloproteinase)]]
[[Category: hydrolase (metalloproteinase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:12:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:42:25 2008''

Revision as of 02:42, 31 March 2008


PDB ID 5tln

Drag the structure with the mouse to rotate
, resolution 2.3Å
Ligands: , ,
Activity: Thermolysin, with EC number 3.4.24.27
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS


About this Structure

5TLN is a Single protein structure of sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA.

Reference

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:7317361

Page seeded by OCA on Mon Mar 31 05:42:25 2008

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